The world economy is under great pressure due to the outbreak of COVID-19, and the situation may turn out to be a big wake up call for global supply chain management. Over the past three decades, despite some setbacks, supply chains in most industries have seen increasing global divisions of labor, which also explains why COVID-19 is having such a great impact on global supply chains. What changes will happen in global supply chains after COVID-19? And how should we respond to the changes?